Myocardial Infarction
About the Disease
Myocardial Infarction, also known as heart attack, is related to lipoprotein quantitative trait locus and cardiovascular system disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Myocardial Infarction is MIAT (Myocardial Infarction Associated Transcript), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include Bone and Limb.
Common Targets
Protein Kinase B (PKB/Akt) (nonspecified subtype) | G2158 | Serine/threonine-protein kinase (PAK) (nonspecified subtype) | Tyrosine-Protein Kinases Src (nonspecified subtype) | G79913 | G5196 | G56829 | G6548 | P16092 | G63895 | G23149 | G1268 | G1295 | G3697 | G441168 | G727 | G5028 | G80157 | G54664 | G10452 | G57451 | G116511 | G59272 | G139760 | G2053 | G9830 | G2100 | G5023 | G84639 | G169611 | G7376 | G5293 | G9037 | G387103 | G716 | G11173 | G142 | G1893 | G3672 | G102724168 | Interleukin-1 (nonspecified subtype) | G3958 | G2626 | G84940 | G55102 | G5726 | G1734 | G51129 | Calpain (nonspecified subtype) | G183 | G217 | G4648 | P42190 | G140775 | G4049 | G2099 | G241 | G101 | G1432 | G4314 | G4524 | G2162 | G2288 | G4921 | G8882 | G5802 | G6332 | G1586 | G6778 | G1902 | G728358 | G7528 | G8470 | G2784 | G10320 | G29119 | G3240 | G2643 | G10 | G7852 | G23293 | G2535 | G26074 | G5321 | G2688 | G27129 | G27245 | G406 | G10533 | G9370 | G5733 | Serum/glucocorticoid regulated kinase (Sgk) (nonspecified subtype) | G151 | G5243 | G8567 | G5742 | Bone Morphogenetic Protein Receptor Type I (nonspecified subtype) | G1581 | G5739 | G3609 | G3827 | G2701 | G101928923 | G126133 | Cyclophilins (nonspecified subtype) | G6525 | G1735 | G22937 | G5029 | G846 | G10221 | G105370614 | G3156 | G9817 | G4869 | G26534 | G100506393 | Rho GTPase (nonspecified subtype) | G5291 | G3566 | G64798 | G43 | G842 | G5743 | G2065 | G5719 | Endothelin-Converting Enzymes (ECE) (nonspecified subtype) | G134 | G284904 | P16704 | G401494 | G187 | G79754 | G9429 | G3383 | G116519 | G6352 | G4286 | G22834 | G23411 | G26086 | G541472 | G6722 | G7224 | G7511 | G50848 | Glycogen phosphorylase (nonspecified subtype) | G1282 | G5535 | G3673 | P6884 | G5352 | G57608 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | G85363 | G80790 | G52 | G10587 | RyR2/FKBP12.6 Complex | G1543 | G7512 | G7639 | G10062 | P40594 | G51393 | G136 | G8321 | G84033 | G8622 | G23294 | G5244 | G84824 | G3630 | G7421 | G2321 | G5024 | G8600 | G8913 | G91544 | IL-1 Receptor (nonspecified subtype) | G1848 | G4318 | G2811 | G3290 | G2165 | G26035 | G5533 | G9472 | G9839 | G4041 | G7058 | G4629 | G115265 | G2022 | G23603 | G2357 | G100048912 | G929 | G6820 | G6581 | G7046 | G2147 | G3849 | G399814 | G729230 | G841 | Integrin Receptor (nonspecified subtype) | G23261 | G10544 | G10746 | G135 | G6850 | G23022 | G5152 | G5481 | G4233 | G440101 | G5334 | G9156 | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | G19 | G2152 | G23228 | G84830 | G949 | Glutamate Transporter (nonspecified subtype) | G1803 | G2120 | G1236 | Sodium channel (nonspecified subtype) | G4519 | G2159 | G81619 | G6648 | G84034 | G958 | G11194 | G6272 | G407012 | G9446 | Neurotrophic Factor (nonspecified subtype) | G5806 | G3791 | G406904 | G7498 | G23328 | G578 | cGMP Phosphdiesterase (PDE) (nonspecified subtype) | G4914 | G231 | G4846 | G255738 | G5770 | G protein-Coupled Inwardly-Rectifying Potassium Channel (GIRK) (nonspecified subtype) | G64897 | G775 | G2242 | G9294 | G406932 | G7097 | G7189 | G26959 | G2932 | G93974 | G406948 | G3248 | Guanylate cyclase (nonspecified subtype) | G590 | P16126 | Liver Bile Transporters (LBAT) (nonspecified subtype) | G5020 | G100526835 | P5561 | G8626 | G952 | G10788 | P24881 | G3586 | G649 | G155 | G5054 | G10059 | Gap junction Connexin ( (nonspecified subtype) | G2876 | G105375745 | G57619 | G65264 | Oxysterols receptor LXR (nonspecified subtype) | G407013 | G1910 | G23263 | G23609 | G406949 | G1816 | G100874095 | G9971 | G1558 | G6403 | G3988 | G836 | G3553 | G3689 | G406950 | G80350 | G81492 | G2196 | G9780 | G345 | G145748 | G2243 | G51135 | G10791 | G4544 | G80975 | G29774 | G6943 | G101928079 | G1066 | G1591 | G4313 | G4985 | G54535 | G2828 | G3569 | G6597 | Adenylate Cyclase (nonspecified subtype) | G5126 | G53345 | G100287329 | G406991 | G6274 | G51086 | G80003 | G11099 | P5756 | G84439 | G2624 | G23301 | G2646 | G140 | G1482 | G79018 | G5687 | G581 | Integrin alphaIIbbeta3 (fibrinogen gpIIb/IIIa) receptor | G5340 | G59350 | G8654 | G5734 | G3356 | G6262 | G3676 | G6532 | G2322 | G11022 | G406937 | G84722 | G931 | G5836 | G3486 | G25902 | G55187 | G406907 | G407015 | G7422 | G4878 | G24 | G5287 | G1192 | G153 | G166614 | Na+/K+-ATPase (nonspecified subtype) | G490 | G5979 | G4311 | G23576 | G10287 | G5601 | K(ATP) Channel (nonspecified subtype) | G146691 | G2309 | G5175 | Inhibitory kappaB Kinase (IKK) (nonspecified subtype) | G6387 | G3760 | G1577 | G7010 | G101928165 | G11069 | G6775 | G1952 | G706 | G55331 | G10461 | G111 | G1812 | G857 | G8701 | G2817 | G9448 | 15-Lipoxygenase (nonspecified subtype) | G64240 | G7364 | G5327 | G5476 | G5506 | G120227 | KCNQ Channels (K(v) 7) (nonspecified subtype) | G4016 | G100379251 | G1667 | G2166 | G835 | G5580 | G3558 | beta-Adrenoceptor (nonspecified subtype) | G22802 | G7391 | G27030 | G3458 | G2833 | G137682 | P6348 | G1769 | G2194 | G6554 | G7015 | G202333 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | Elastase (nonspecified subtype) | G157273 | G185 | G2153 | G90 | G2244 | G4843 | G23051 | G80007 | G1284 | G140628 | G64805 | Prostanoid TP receptor (nonspecified subtype) | Serine protease (nonspecified subtype) | G4035 | G57535 | G3717 | G3990 | G6948 | G101928272 | G6885 | G23053 | G3158 | G11120 | G356 | Caspase (nonspecified subtype) | G7124 | G8876 | G55191 | G4322 | G833 | G9475 | G1361 | G1912 | G2101 | G79832 | G260425 | Ectonucleotide pyrophosphatase/phosphodiesterase (E-NPP) (nonspecified subtype) | P6058 | G23621 | G9564 | G154 | G4739 | G406908 | G54542 | G10234 | G9734 | G3159 | G58472 | G64241 | G148281 | G3762 | G7428 | G586 | G4547 | G51334 | L-Type calcium channel (nonspecified subtype) | G152273 | G378938 | G114 | G6910 | G6927 | G23414 | G2819 | G2982 | G57215 | G158401 | G79652 | G3579 | G6323 | G3718 | G23271 | G1027 | P5753 | G3920 | G22806 | G27031 | Heat shock protein 70 (nonspecified subtype) | G1559 | G51141 | G1230 | P13475 | G126859 | G6280 | G3716 | G1906 | G7296 | P13024 | G1573 | Histone deacetylase (nonspecified subtype) | G407046 | G4140 | G1969 | G7273 | G2638 | G1234 | G2358 | G51703 | G1378 | G144165 | G54210 | G5444 | P16740 | G401014 | G7399 | G55759 | G105371773 | G54620 | G54920 | G10599 | G10724 | G1116 | Poly [ADP-ribose] polymerase (nonspecified subtype) | G199692 | G2057 | G54658 | G348 | G8527 | G53637 | G114548 | Vasopressin Receptor (nonspecified subtype) | P5757 | G6583 | G406909 | G51185 | G392232 | G4282 | G7226 | G64135 | G1499 | G5167 | G8424 | G3358 | G3576 | G375567 | G2697 | G2846 | G3565 | G23274 | G100131213 | G5532 | P22884 | G6405 | G7060 | G2028 | G7157 | G10320 | G10038 | G147841 | G83988 | G8633 | G871 | G100507163 | G2869 | G28951 | G3690 | G7092 | G7415 | G335 | G177 | G57582 | G355 | Adenosine receptor (nonspecified subtype) | G4088 | G2160 | G84444 | G5534 | G55705 | G861 | G55970 | G3082 | G153090 | G406971 | G1814 | G186 | G2081 | G5328 | G5602 | G80325 | Nitric oxide synthase (NOS) (nonspecified subtype) | G351 | G23092 | G79602 | G4907 | G79068 | G23417 | G240 | G60485 | G3818 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 (nonspecified protein) | G164 | G4317 | G3570 | G1889 | G4363 | G79148 | G57105 | G3146 | G6347 | G6422 | G407048 | G728 | G8645 | G55843 | G116328 | G4862 | G2740 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype) | G4881 | G5027 | G101928376 | Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype) | G7099 | G834 | G9002 | G338 | G596 | G64761 | Potassium Channels (nonspecified subtype) | G440590 | G5045 | G8529 | G54583 | G940 | G5648 | G3172 | G51206 | G245711 | G100507308 | G387787 | G79047 | G105372161 | G7040 | G2149 | G7515 | G55973 | Gap Junction Protein (nonspecified subtype) | Phosphodiesterase 8 (nonspecified subtype) | G51530 | G11103 | G6310 | G144347 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | Arginase (nonspecified subtype) | G7093 | G2104 | G105378678 | Angiotensin receptor (AT) (nonspecified subtype) | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | G1585 | G7941 | G5021 | G25 | G5523 | G407049 | G3654 | G51103 | G10019 | G54828 | G10443 | G3705 | G930 | G6427 | G4129 | G2692 | G6584 | G3909 | G221458 | G51284 | G2155 | G84913 | G10257 | G1401 | G8737 | P10999 | Rho kinase (ROCK) (nonspecified subtype) | G28 | G135228 | G6331 | G6774 | G4056 | G4312 | G125919 | G29922 | G57480 | G1607 | G6934 | G657 | G406913 | G6915 | G143872 | G153443 | G4048 | G2904 | G710 | G4540 | G2247 | G7448 | G10449 | G4018 | G22864 | G10411 | G5972 | G4567 | P29419 | G1594 | G22955 | G23564 | Calcium/calmodulin-dependent protein kinase type II (CaMK-II) | G3707 | P5859 | G1524 | G2030 | G101928448 | 3-Ketoacyl-CoA Thiolase (3-KAT) (nonspecified subtype) | G64840 | G23005 | G23410 | G5266 | G580 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | G22808 | G5144 | G54892 | G5581 | G7417 | G253943 | G257101 | G4353 | G5592 | G10891 | G5728 | G156 | G27306 | G18 | G193629 | G7804 | G4920 | G90324 | G5737 | G6790 | G4790 | G5136 | G3091 | G1636 | G695 | G20 | G4988 | G83605 | G55022 | G1215 | G6647 | G8639 | G102723340 | G387 | G170961 | G1909 | G100505832 | G839 | G57591 | Superoxide dismutase (SOD) (nonspecified subtype) | G64072 | G55153 | Phosphodiesterase (nonspecified subtype) | G6311 | G3633 | G384 | G221955 | G9033 | G55884 | Glutamate Receptor Ionotropic (nonspecified subtype) | G374470 | G574501 | G6097 | G4682 | G79674 | G5445 | G9388 | G9457 | G3620 | G375056 | G1576 | G5890 | G246 | G11083 | G627 | G6546 | G23566 | G54805 | G102723487 | G1269 | G140701 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | G4986 | G63892 | G6916 | G7351 | G2870 | G10574 | G9575 | G11255 | G1991 | G2621 | G2642 | Glutathione peroxidase (nonspecified subtype) | G6401 | G3693 | G1535 | G2161 | G4568 | G79987 | G9718 | P16683 | G3557 | G4780 | G81786 | Na+/Ca2+ Exchanger (NCX) (nonspecified subtype) | G6326 | G3949 | G1843 | G221656 | G7473 | G6524 | G8613 | G105370176 | G3684 | G53919 | G57547 | G1396 | G6696 | G1012 | G103 | G7292 | G2191 | G22900 | G23075 | G51548 | G342372 | G1813 | G4306 | G341676 | G1557 | G5142 | G8912 | G6813 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | G624 | G79800 | G2475 | G26058 | G5336 | G5465 | G1071 | G222 | G2706 | G55669 | G2931 | G23097 | G7881 | G105377185 | G6720 | G432 | G8840 | G55094 | G5599 | G10611 | Heat shock protein 90 (nonspecified subtype) | G6348 | G22933 | G101927728 | G9745 | G629 | P5755 | Calcium channel (nonspecified subtype) | G675 | G23037 | G57057 | G1445 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | G152485 | G79991 | G2693 | G55553 | P5760 | G8078 | G840 | G5573 | G11342 | P18508 | G390174 | Protein kinase C (nonspecified subtype) | G221692 | G5468 | G148 | G7450 | G4938 | G2335 | G254102 | G4023
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• protein biological mechanisms;
• its importance;
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• expression level;
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